Research Funding

EU Research Grants

Ongoing projects in 2019 with funding of more than 1 million euros

Topic	Project Head	Amount Granted
Efficacy and safety of thrombectomy in stroke with extended lesion and extended time window: a randomized, controlled trial (TENSION)	Prof. Dr. Martin Bendszus Dr. Steffen Luntz	2,455 KEUR
Establishment and Exploitation of a European-Latin American Research Consortium towards Eradication of Preventable Gallbladder Cancer (EULAT Eradicate GBC)	Prof. Dr. Justo Lorenzo Bermejo	2,362 KEUR
Antibodies against Nogo-A to enhance plasticity, regeneration and functional recovery after acute spinal cord injury, a multicenter European clinical proof of concept trial (NISCI)	Prof. Dr. Norbert Weidner Dr. Steffen Luntz Dr. Tanja Weiss	2,037 KEUR
Penumbral Rescue by Normobaric O=O Administration in Patients With Ischaemic Stroke and Target Mismatch ProFile: A Phase II Proof-of-Concept Trial (PROOF)	Dr. Steffen Luntz	1,351 KEUR
Reconciliation of Cohort Data for Infectious Diseases (RECODID)	PD Dr. Thomas Jänisch	1,237 KEUR
Added Value for Oral Care (ADVOCATE)	Prof. Dr. Dr. Stefan Listl	1,203 KEUR
A global alliance for Zika virus control and prevention (ZIKAlliance)	Dr. Thomas Jänisch	1,111 KEUR

Ongoing ERC Grants in 2019

Topic	Project Head	Grant	Amount Granted
Dry season P. falciparum reservoir (DrySeasonPf)	Dr. Silvia Portugal	Starting Grant	1,500 KEUR
Hypothalamic Mechanisms of Thermal Homeostasis and Adaptation (Acclimatize)	Prof. Dr. Jan-Erik Siemens	Consolidator Grant	1,903 KEUR

Research Grants from the German Federal Government

Ongoing projects in 2019 with funding of more than 1 million euros

Topic	Spokesperson	Total Amount Granted
German Center for Cardiovascular Research	Prof. Dr. Hugo Katus	14,500 KEUR
German Center for Lung Research	Prof. Dr. Markus Mall	13,316 KEUR
German Center for Infection Research	Prof. Dr. Hans-Georg Kräusslich	13,033 KEUR
HiGHmed Medical Informatics Consortium, buildup and networking phase	Prof. Dr. Roland Eils Prof. Dr. Christoph Dieterich	9,266 KEUR
Adaptive Radiotherapy with Ion Beams (ARTEMIS)	Prof. Dr. Jürgen Debus	6,739 KEUR
SMART-CARE: A systems medicine approach to stratify the relapse of cancer	Prof. Dr. Jeroen Krijgsveld Prof. Dr. Karsten Müller-Tidow Prof. Dr. Petra Knaup-Gregori Prof. Dr. Julio Saez-Rodriguez Prof. Dr. Peter Schirmacher Prof. Dr. Andreas von Deimling Dr. Sascha Dietrich	3,500 KEUR
An integrated systems medicine approach to personalized and targeted therapy in leukemia and lymphoma (SYMPATHY)	Dr. Sascha Dietrich	3,085 KEUR
Improvement of functional outcomes for patients with newly diagnosed grade II or III glioma with co-deletion of 1p/19q - IMPROVE CO-DEL: a NOA trial	Prof. Dr. Wolfgang Wick	2,948 KEUR
Reducing malnutrition in infants through an integrated agricultural project with groups of women: A group-randomized interventional study in rural Bangladesch (FAARM)	Dr. Sabine Gabrysch	2,926 KEUR
German Center for Diabetes Research	Prof. Dr. Peter Nawroth	2,250 KEUR
National cohorts, health survey 2. Förderphase	Prof. Dr. Hans-Ulrich Kauczor Prof. Dr. Till Bärnighausen	2,032 KEUR
Liposomes as a platform technology for the oral application of macromolecular active substances (LipOra)	Dr. Philipp Uhl Dr. Max Sauter	1,870 KEUR
Development of a novel lipid-lowering agent to reduce cardiovascular risk with hypercholesterolemia and metabolic syndrome (PrimaLiveR)	Dr. Volker Cleeves	1,782 KEUR
Randomized, controlled, multicenter therapy study on the initial treatment for the initial manifestation of infantile idiopathic nephrotic syndrome with Mycophenolatmofetil versus Prednison (INTENT-Studie)	Prof. Dr. Burkhard Tönshoff	1,682 KEUR
Competence-oriented learning, teaching and examinations in medicine; sub-project of the Heidelberg Faculty of Medicine (MERLIN II)	Dr. Andreas Möltner	1,420 KEUR
Optimizing the cooperation between family doctors and psychotherapists: A study on the implemention of video consultations (PROVIDE)	PD Dr. Markus Haun	1,286 KEUR
The cross-generational cycle of abuse in families: Causes and prevention through measures taken by the healthcare system and social services – four sub-projects (UBICA II)	Prof. Dr. Sabine Herpertz Prof. Dr. Svenja Taubner Prof. Dr. Beate Ditzen Dr. med. Steffen Luntz	1,225 KEUR
Research into promoting help-seeking behavior by adolescents with mental problems through the use of new media; central project VCP (Pro-HEAD)	Prof. Dr. Michael Kaess	1,191 KEUR
German Biobanks Allianz / BBMRI.de – at Heidelberg (GBS)	Prof. Dr. Peter Schirmacher	1,174 KEUR
Development and evaluation of content-specific interventions to improve the healthcare of asylum-seekers (RESPOND)	Dr. Kayvan Bozorgmehr	1,131 KEUR

Participation in five German Health Research Centers

German Center for Cardiovascular Research
German Center for Lung Research
German Center for Infection Research
German Center for Diabetes Research
German Center for Translational Cancer Research

Collaborative Research Centers of the German Research Foundation

	Title	Spokesperson
CRC 1118	Reactive metabolites as the cause of diabetic complications	Prof. Dr. Peter Nawroth
CRC 1129	Integrative Analysis of Pathogen Replication and Spread	Prof. Dr. Hans-Georg Kräusslich
CRC 1134	Functional ensembles: cellular components, patterned activity and plasticity of co-active neurons in local networks	Prof. Dr. Andreas Draguhn
CRC 1158	From nociception to chronic pain: Structural functional features of neuronal pathways and their reorganization	Prof. Dr. Rohini Kuner
CRC 1389	Overcoming the resistance to treatment of glioblastomas	Prof. Dr. Wolfgang Wick
CRC-TRR 83	Molecular architecture and cellular functions of lipid-protein complexes	Prof. Dr. Thomas Söllner
CRC-TRR 156	The skin as sensor and effector organ orchestrating local and systemic immune responses	Prof. Dr. Alexander Enk
CRC-TRR 179	Determinants and dynamics of elimination versus persistance of hepatitis virus infection	Prof. Dr. Ralf Bartenschlager
CRC-TRR 209	Liver cancer – new mechanistic and therapeutic concepts in a solid tumor model	Prof. Dr. Peter Schirmacher

	Title	Sites
CRC 873	Maintenance and differentiation of stem cells in development and disease	Heidelberg
CRC 1036	Cellular surveillance and damage response	Heidelberg
SFB 1324	Mechanisms and functions of Wnt signaling	Heidelberg
SFB 1366	Vascular control of organ function	Heidelberg
SFB-TRR 79	Active substances for regenerating tissue in sytemically diseased bones	Gießen, Heidelberg, Dresden
SFB-TRR 186	Molecular switch for spatial and kinetic regulation of cellular signal transmission	Heidelberg, Berlin
SFB-TRR 152	TRiPs to Homeostasis: Maintenance of Body Homeostasis by Transient Receptor Potential Channel Modules	München, Homburg, Freiburg, Heidelberg

Other major German Research Foundation projects

Ongoing projects in 2019 with funding of more than 500,000 euros

Topic	Spokesperson	Total Grant
Cluster of Excellence CellNetworks Junior Research Group: Viral Infection	Dr. Pierre-Yves Lozach	1,418 KEUR
Emmy Noether mTOR-dependent growth monitoring in the heart	Dr. Mirko Völkers	1,268 KEUR
Emmy Noether Spatial periodicity of the grid cell: Necessary cellular interactions in development and functional relevance	Dr. Kevin Allen	1,217 KEUR
Emmy Noether Treatable metabolic weak spots in leukemic stem cells	Dr. med. Simon Raffel	1,153 KEUR
Clinical Trial RESPONDER – Diagnosis of a pathogenic complete remission through a vacuum-assisted biopsy after neoadjuvenant chemotherapy for breast cancer	Prof. Dr. Jörg Heil	1,002 KEUR
individual Research Grant Prospektive evaluation of residual disease as a surrogate for survival endpoints for patients with acute myelotic leukemia who have received intensive care	Prof. Dr. Richard Schlenk	941 KEUR
Clinical Trial Reducing the post-operation rate of hernias through small-stitch abdominal wall closures without versus with prophylactic net implantation (HULC)	PD Dr. André Mihaljevic	901 KEUR
Research Group 2936 Climate change and health in Africa south of the Sahara; TP ZP 01: Development and analysis of population cohorts in Burkina Faso and Kenya	Prof. Dr. Till Bärnighausen	637 KEUR
individual Research Grant Secondary use of clinical data for research and care – ethical, societal and legal aspects	Prof. Dr. Eva Winkler	615 KEUR
Research Group 2407 Research on the degeneration and regeneration of articular cartilage and subchondral bones in osteoarthrosis (ExCarBon)	Prof. Dr.Wiltrud Richter	537 KEUR
individual Research Grant MicroRNA regulation of the glucocorticoid-induced autophagia and progression of the ductal adenocarcinoma of the pancreas	Prof. Dr. Ingrid Herr	533 KEUR
individual Research Grant Integrative analysis of nuclear division mechanisms in the malaria parasite	Dr. Julien Guizetti	532 KEUR
individual Research Grant One-pot shotgun cell biology	Prof. Dr. Michael Knop	531 KEUR
individual Research Grant Exploring novel molecular mechanisms of TSC22D4 in the development of diabetes mellitus	Dr. Bilgen Ekim Üstünel	516 KEUR
individual Research Grant Metabolic processes in rheumatoid arthritis: CD8+T-cells develop their diagnostic and therapeutic potential	Dr. Margarida Souto-Carneiro	510 KEUR
Research Group 2289 Calcium homeostasis in neuroinflammation and degeneration: New approaches for the treatment of multiple sclerosis? (TP1 and Z2)	Prof. Dr. Ricarda Diem	506 KEUR

Projects with other sponsors

Ongoing projects in 2019 with funding of more than one million euros

Topic	Spokesperson	Total Grant
Dietmar-Hopp-Stiftung Heidelberg concept to cure multiple myeloma	Prof. Dr. Hartmut Goldschmidt	12,566 KEUR
Dietmar-Hopp-Stiftung Exploratory study to identify predicative biomarket signatures in patients with advanced non-small cell lung canceer (NSCLC)	Prof. Dr. Dirk Jäger	5,808 KEUR
Dietmar-Hopp-Stiftung Pilot project to develop a personalized, celluar immune therapy for solid tumor diseases	Prof. Dr. Dirk Jäger	2,879 KEUR
Federal Joint Committee (G-BA) Improving the care of people with rare diseases by implementing measures consented to in the national action plan (NAMSE) / TRANSLATE-NAMSE	Prof. Georg Friedrich Hoffmann PD Dr. Daniela Choukair	2,428 KEUR
Chica und Heinz Schaller Stiftung Junior research group: Membrane biology of viral infection	Dr. Petr Chlanda	1,826 KEUR
Chica und Heinz Schaller Stiftung Junior research group: Laboratory of neural circuits and behavior	Claudio D. Acuna Goycolea, Ph.D.	1,826 KEUR
Chica und Heinz Schaller Stiftung Junior research group: Neuron-Glia Interactions in Neural Circuits	Dr. Amit Agarwal	1,785 KEUR
Dietmar Hopp Stiftung Newborn screening – optimization of diagnostic processes	Prof. Dr. Georg F. Hoffmann	1,785 KEUR
Chica und Heinz Schaller Stiftung Junior research group: Stem cell-derived culture models for hepatitis E virus studies	Viet Loan Dao Thi, Ph.D.	1,780 KEUR
Deutsche Krebshilfe Phase I/II Umbrella Study of molecular adapted treatments in combination with radiation therapy for patients with newly diagnosed glioblastoma without MGMT MGMT Promotor hypermethylation: NCT Neuro Master Match (N2M2)	Prof. Dr. Wolfgang Wick	1,500 KEUR
Chica und Heinz Schaller Stiftung Junior research groups CellNetworks	Prof. Dr. Hans-Georg Kräusslich	1,500 KEUR
Baden-Württemberg Ministry for Science, Research and Art Junior reseach group for pediatric precision oncology	Prof. Dr. Stefan Pfister Dr. Kristian Pajtler	1,499 KEUR
Klaus Tschira Stiftung Etablishment of a sustainable real laboratory for interdisciplinary and translational research in the field of mathematical modelling and simulation in ophthalmology	Prof. Dr. Gerd Auffarth	1,494 KEUR
Joint Federal Committee (G-BA) Mind: Pregnancy – Online-based mindfulness intervention to strengthen the mental stability of pregnant women and to promote physiologic birth	PD Dr. Stephanie Wallwiener	1,370 KEUR
Dietmar Hopp Stiftung Further development of newborn screening	Prof. Dr. Georg F. Hoffmann	1,160 KEUR
Joint Federal Committee (G-BA) Ensuring care continuity: Patient-oriented admission and discharge management in general-practitioner practices and hospitals	Prof. Dr. Joachim Szecsenyi Prof. Dr. Meinhard Kieser	1,113 KEUR
Dietmar Hopp Stiftung PACMAN – Intravenous vs. epidural analgesia to reduce the frequence of gastrointestinal complications after an elective pancreatoduodectomy	Dr. Philipp Knebel	1,079 KEUR
Joint Federal Committee (G-BA) Participation-related goal achievement through remedies and equipment with mobility-restricting paralysis syndromes (NeuroMoves)	Prof. Dr. Norbert Weidner PD Dr. Rüdiger Rupp Prof. Dr. Michael Wensing	1,054 KEUR
Else Kröner-Fresenius-Stiftung Else Kröner-Research Schools: Heidelberg Research School for Neurooncology	Prof. Dr. Wolfgang Wick	1,000 KEUR

Junior Development Programs at the Faculty of Medicine

Program	Goal/Content	Support
MD/PhD	Structured doctoral program in biology, natural sciences and clinical work for students of human medicine and dentistry after they have completed the first part of the state examination in medicine or the preliminary dental medicine examination	6 newly admitted students
Physician Scientist	Protected research time with simultaneous relief from clinical work for physicians who have obtained their doctorates. Three-year program, the Medical Faculty finances two years of research time. The third year is for clinical advanced training and is financed by the department.	15 places approved
Rotation Jobs Dentistry	Support for junior researchers in dentistry	1 place approved
Curriculum Clinical Research	Modular qualification program for co-workers who are involved in the implementation of clinical trials.	Absorption of the qualification costs
MEDISS (Medical Structured Scientific Program)	Faculty-wide, structural doctoral program to support the academic exchange with experienced scientists, good scientific practice, and specialized courses	For all medical and dental PhD students

Gender Equality

Program	Goal/Content	Support
Olympia Morata	Postdoctoral qualification program qualified female researchers/physicians; protected research time: 2 years, 50% of the position	4 approvals
Rahel Goitein-Straus	Support for the transition of female physicians/researchers to their first independent research work; protected research time: 1 year, 50% of the position	4 approvals
Short-Term Grants	Support for research activities by women during or even after their residencies; protected research time: 3-6 months	4 approvals
Mentoring Program	For female researchers and physicians with modular management training and competency seminars as well as mentoring by experienced leaders	10 participants

Internal Research Support Programs

Program	Goal/Content	Support
"Third-Party Funding“ Bonus Program	Researchers will receive a bonus for the acquisition of third-party funding for biomedical projects, which were awarded in a recognized evaluation procedure	About 4 million euros
Bonus Program Leading Publications	Bonus for publications on research results which were predominantly developed at a facility of the Medical Faculty at the University of Heidelberg	About 200 thousand euros
Research / Investment Funds	Funding from the German Research Foundation (DFG) overhead financing program to reinforce the research infrastructure. In 2019, the focus was on large-scale research equipment.	Up to 2 million euros

Annual Report 2019

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