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Annual Report 2019

Research Funding

EU Research Grants

Ongoing projects in 2019 with funding of more than 1 million euros


Project Head

Amount Granted

Efficacy and safety of thrombectomy in stroke with extended lesion and extended time window: a randomized, controlled trial (TENSION)

Prof. Dr. Martin Bendszus
Dr. Steffen Luntz

2,455 KEUR

Establishment and Exploitation of a European-Latin American Research Consortium towards Eradication of Preventable Gallbladder Cancer (EULAT Eradicate GBC)

Prof. Dr. Justo Lorenzo Bermejo

2,362 KEUR

Antibodies against Nogo-A to enhance plasticity, regeneration and functional recovery after acute spinal cord injury, a multicenter European clinical proof of concept trial (NISCI)

Prof. Dr. Norbert Weidner
Dr. Steffen Luntz
Dr. Tanja Weiss

2,037 KEUR

Penumbral Rescue by Normobaric O=O Administration in Patients With Ischaemic Stroke and Target Mismatch ProFile: A Phase II Proof-of-Concept Trial (PROOF)

Dr. Steffen Luntz

1,351 KEUR

Reconciliation of Cohort Data for Infectious Diseases (RECODID)

PD Dr. Thomas Jänisch

1,237 KEUR

Added Value for Oral Care (ADVOCATE)

Prof. Dr. Dr. Stefan Listl

1,203 KEUR

A global alliance for Zika virus control and prevention (ZIKAlliance)

Dr. Thomas Jänisch

1,111 KEUR

Ongoing ERC Grants in 2019


Project Head


Amount Granted

Dry season P. falciparum reservoir (DrySeasonPf)

Dr. Silvia Portugal

Starting Grant

1,500 KEUR

Hypothalamic Mechanisms of Thermal Homeostasis and Adaptation (Acclimatize)

Prof. Dr. Jan-Erik Siemens

Consolidator Grant

1,903 KEUR

Research Grants from the German Federal Government

Ongoing projects in 2019 with funding of more than 1 million euros



Total Amount Granted

German Center for Cardiovascular Research

Prof. Dr. Hugo Katus

14,500 KEUR

German Center for Lung Research

Prof. Dr. Markus Mall

13,316 KEUR

German Center for Infection Research

Prof. Dr. Hans-Georg Kräusslich

13,033 KEUR

HiGHmed Medical Informatics Consortium, buildup and networking phase

Prof. Dr. Roland Eils
Prof. Dr. Christoph Dieterich

9,266 KEUR

Adaptive Radiotherapy with Ion Beams (ARTEMIS)

Prof. Dr. Jürgen Debus

6,739 KEUR

SMART-CARE: A systems medicine approach to stratify the relapse of cancer

Prof. Dr. Jeroen Krijgsveld
Prof. Dr. Karsten Müller-Tidow
Prof. Dr. Petra Knaup-Gregori
Prof. Dr. Julio Saez-Rodriguez
Prof. Dr. Peter Schirmacher
Prof. Dr. Andreas von Deimling
Dr. Sascha Dietrich

3,500 KEUR

An integrated systems medicine approach to personalized and targeted therapy in leukemia and lymphoma (SYMPATHY)

Dr. Sascha Dietrich

3,085 KEUR

Improvement of functional outcomes for patients with newly diagnosed grade II or III glioma with co-deletion of 1p/19q - IMPROVE CO-DEL: a NOA trial

Prof. Dr. Wolfgang Wick

2,948 KEUR

Reducing malnutrition in infants through an integrated agricultural project with groups of women: A group-randomized interventional study in rural Bangladesch (FAARM)

Dr. Sabine Gabrysch

2,926 KEUR

German Center for Diabetes Research

Prof. Dr. Peter Nawroth

2,250 KEUR

National cohorts, health survey
2. Förderphase

Prof. Dr. Hans-Ulrich Kauczor
Prof. Dr. Till Bärnighausen

2,032 KEUR

Liposomes as a platform technology for the oral application of macromolecular active substances (LipOra)

Dr. Philipp Uhl
Dr. Max Sauter

1,870 KEUR

Development of a novel lipid-lowering agent to reduce cardiovascular risk with hypercholesterolemia and metabolic syndrome (PrimaLiveR)

Dr. Volker Cleeves

1,782 KEUR

Randomized, controlled, multicenter therapy study on the initial treatment for the initial manifestation of infantile idiopathic nephrotic syndrome with Mycophenolatmofetil versus Prednison (INTENT-Studie)

Prof. Dr. Burkhard Tönshoff

1,682 KEUR

Competence-oriented learning, teaching and examinations in medicine; sub-project of the Heidelberg Faculty of Medicine (MERLIN II)

Dr. Andreas Möltner

1,420 KEUR

Optimizing the cooperation between family doctors and psychotherapists: A study on the implemention of video consultations (PROVIDE)

PD Dr. Markus Haun

1,286 KEUR

The cross-generational cycle of abuse in families: Causes and prevention through measures taken by the healthcare system and social services – four sub-projects (UBICA II)

Prof. Dr. Sabine Herpertz
Prof. Dr. Svenja Taubner
Prof. Dr. Beate Ditzen
Dr. med. Steffen Luntz

1,225 KEUR

Research into promoting help-seeking behavior by adolescents with mental problems through the use of new media; central project VCP (Pro-HEAD)

Prof. Dr. Michael Kaess

1,191 KEUR

German Biobanks Allianz / BBMRI.de – at Heidelberg (GBS)

Prof. Dr. Peter Schirmacher

1,174 KEUR

Development and evaluation of content-specific interventions to improve the healthcare of asylum-seekers (RESPOND)

Dr. Kayvan Bozorgmehr

1,131 KEUR

Participation in five German Health Research Centers

  • German Center for Cardiovascular Research
  • German Center for Lung Research
  • German Center for Infection Research
  • German Center for Diabetes Research
  • German Center for Translational Cancer Research

Collaborative Research Centers of the German Research Foundation




CRC 1118

Reactive metabolites as the cause of diabetic complications

Prof. Dr. Peter Nawroth

CRC 1129

Integrative Analysis of Pathogen Replication and Spread

Prof. Dr. Hans-Georg Kräusslich

CRC 1134

Functional ensembles: cellular components, patterned activity and plasticity of co-active neurons in local networks

Prof. Dr. Andreas Draguhn

CRC 1158

From nociception to chronic pain: Structural functional features of neuronal pathways and their reorganization

Prof. Dr. Rohini Kuner

CRC 1389

Overcoming the resistance to treatment of glioblastomas

Prof. Dr. Wolfgang Wick


Molecular architecture and cellular functions of lipid-protein complexes

Prof. Dr. Thomas Söllner


The skin as sensor and effector organ orchestrating local and systemic immune responses

Prof. Dr. Alexander Enk


Determinants and dynamics of elimination versus persistance of hepatitis virus infection

Prof. Dr. Ralf Bartenschlager


Liver cancer – new mechanistic and therapeutic concepts in a solid tumor model

Prof. Dr. Peter Schirmacher




CRC 873

Maintenance and differentiation of stem cells in development and disease


CRC 1036

Cellular surveillance and damage response


SFB 1324

Mechanisms and functions of Wnt signaling


SFB 1366

Vascular control of organ function



Active substances for regenerating tissue in sytemically diseased bones

Gießen, Heidelberg, Dresden


Molecular switch for spatial and kinetic regulation of cellular signal transmission

Heidelberg, Berlin


TRiPs to Homeostasis: Maintenance of Body Homeostasis by Transient Receptor Potential Channel Modules

München, Homburg, Freiburg, Heidelberg

Other major German Research Foundation projects

Ongoing projects in 2019 with funding of more than 500,000 euros



Total Grant

Cluster of Excellence
CellNetworks Junior Research Group: Viral Infection

Dr. Pierre-Yves Lozach

1,418 KEUR

Emmy Noether
mTOR-dependent growth monitoring in the heart

Dr. Mirko Völkers

1,268 KEUR

Emmy Noether
Spatial periodicity of the grid cell: Necessary cellular interactions in development and functional relevance

Dr. Kevin Allen

1,217 KEUR

Emmy Noether
Treatable metabolic weak spots in leukemic stem cells

Dr. med. Simon Raffel

1,153 KEUR

Clinical Trial
RESPONDER – Diagnosis of a pathogenic complete remission through a vacuum-assisted biopsy after neoadjuvenant chemotherapy for breast cancer

Prof. Dr. Jörg Heil

1,002 KEUR

individual Research Grant
Prospektive evaluation of residual disease as a surrogate for survival endpoints for patients with acute myelotic leukemia who have received intensive care

Prof. Dr. Richard Schlenk

941 KEUR

Clinical Trial
Reducing the post-operation rate of hernias through small-stitch abdominal wall closures without versus with prophylactic net implantation (HULC)

PD Dr. André Mihaljevic

901 KEUR

Research Group 2936
Climate change and health in Africa south of the Sahara; TP ZP 01: Development and analysis of population cohorts in Burkina Faso and Kenya

Prof. Dr. Till Bärnighausen

637 KEUR

individual Research Grant
Secondary use of clinical data for research and care – ethical, societal and legal aspects

Prof. Dr. Eva Winkler

615 KEUR

Research Group 2407
Research on the degeneration and regeneration of articular cartilage and subchondral bones in osteoarthrosis (ExCarBon)

Prof. Dr.Wiltrud Richter

537 KEUR

individual Research Grant
MicroRNA regulation of the glucocorticoid-induced autophagia and progression of the ductal adenocarcinoma of the pancreas

Prof. Dr. Ingrid Herr

533 KEUR

individual Research Grant
Integrative analysis of nuclear division mechanisms in the malaria parasite

Dr. Julien Guizetti

532 KEUR

individual Research Grant
One-pot shotgun cell biology

Prof. Dr. Michael Knop

531 KEUR

individual Research Grant
Exploring novel molecular mechanisms of TSC22D4 in the development of diabetes mellitus

Dr. Bilgen Ekim Üstünel

516 KEUR

individual Research Grant
Metabolic processes in rheumatoid arthritis: CD8+T-cells develop their diagnostic and therapeutic potential

Dr. Margarida Souto-Carneiro

510 KEUR

Research Group 2289
Calcium homeostasis in neuroinflammation and degeneration: New approaches for the treatment of multiple sclerosis? (TP1 and Z2)

Prof. Dr. Ricarda Diem

506 KEUR

Projects with other sponsors

Ongoing projects in 2019 with funding of more than one million euros



Total Grant

Heidelberg concept to cure multiple myeloma

Prof. Dr. Hartmut Goldschmidt

12,566 KEUR

Exploratory study to identify predicative biomarket signatures in patients with advanced non-small cell lung canceer (NSCLC)

Prof. Dr. Dirk Jäger

5,808 KEUR

Pilot project to develop a personalized, celluar immune therapy for solid tumor diseases

Prof. Dr. Dirk Jäger

2,879 KEUR

Federal Joint Committee (G-BA)
Improving the care of people with rare diseases by implementing measures consented to in the national action plan (NAMSE) / TRANSLATE-NAMSE

Prof. Georg Friedrich Hoffmann
PD Dr. Daniela Choukair

2,428 KEUR

Chica und Heinz Schaller Stiftung
Junior research group: Membrane biology of viral infection

Dr. Petr Chlanda

1,826 KEUR

Chica und Heinz Schaller Stiftung
Junior research group: Laboratory of neural circuits and behavior

Claudio D. Acuna Goycolea, Ph.D.

1,826 KEUR

Chica und Heinz Schaller Stiftung
Junior research group: Neuron-Glia Interactions in Neural Circuits

Dr. Amit Agarwal

1,785 KEUR

Dietmar Hopp Stiftung
Newborn screening – optimization of diagnostic processes

Prof. Dr. Georg F. Hoffmann

1,785 KEUR

Chica und Heinz Schaller Stiftung
Junior research group: Stem cell-derived culture models for hepatitis E virus studies

Viet Loan Dao Thi, Ph.D.

1,780 KEUR

Deutsche Krebshilfe
Phase I/II Umbrella Study of molecular adapted treatments in combination with radiation therapy for patients with newly diagnosed glioblastoma without MGMT MGMT Promotor hypermethylation: NCT Neuro Master Match (N2M2)

Prof. Dr. Wolfgang Wick

1,500 KEUR

Chica und Heinz Schaller Stiftung
Junior research groups CellNetworks

Prof. Dr. Hans-Georg Kräusslich

1,500 KEUR

Baden-Württemberg Ministry for Science, Research and Art
Junior reseach group for pediatric precision oncology

Prof. Dr. Stefan Pfister
Dr. Kristian Pajtler

1,499 KEUR

Klaus Tschira Stiftung
Etablishment of a sustainable real laboratory for interdisciplinary and translational research in the field of mathematical modelling and simulation in ophthalmology

Prof. Dr. Gerd Auffarth

1,494 KEUR

Joint Federal Committee (G-BA)
Mind: Pregnancy – Online-based mindfulness intervention to strengthen the mental stability of pregnant women and to promote physiologic birth

PD Dr. Stephanie Wallwiener

1,370 KEUR

Dietmar Hopp Stiftung
Further development of newborn screening

Prof. Dr. Georg F. Hoffmann

1,160 KEUR

Joint Federal Committee (G-BA)
Ensuring care continuity: Patient-oriented admission and discharge management in general-practitioner practices and hospitals

Prof. Dr. Joachim Szecsenyi
Prof. Dr. Meinhard Kieser

1,113 KEUR

Dietmar Hopp Stiftung
PACMAN – Intravenous vs. epidural analgesia to reduce the frequence of gastrointestinal complications after an elective pancreatoduodectomy

Dr. Philipp Knebel

1,079 KEUR

Joint Federal Committee (G-BA)
Participation-related goal achievement through remedies and equipment with mobility-restricting paralysis syndromes (NeuroMoves)

Prof. Dr. Norbert Weidner
PD Dr. Rüdiger Rupp
Prof. Dr. Michael Wensing

1,054 KEUR

Else Kröner-Fresenius-Stiftung
Else Kröner-Research Schools: Heidelberg Research School for Neurooncology

Prof. Dr. Wolfgang Wick

1,000 KEUR

Junior Development Programs at the Faculty of Medicine





Structured doctoral program in biology, natural sciences and clinical work for students of human medicine and dentistry after they have completed the first part of the state examination in medicine or the preliminary dental medicine examination

6 newly admitted students

Physician Scientist

Protected research time with simultaneous relief from clinical work for physicians who have obtained their doctorates. Three-year program, the Medical Faculty finances two years of research time. The third year is for clinical advanced training and is financed by the department.

15 places approved

Rotation Jobs

Support for junior researchers in dentistry

1 place approved

Clinical Research

Modular qualification program for co-workers who are involved in the implementation of clinical trials.

Absorption of the qualification costs

MEDISS (Medical Structured Scientific Program)

Faculty-wide, structural doctoral program to support the academic exchange with experienced scientists, good scientific practice, and specialized courses

For all medical and dental PhD students

Gender Equality




Olympia Morata

Postdoctoral qualification program qualified female researchers/physicians; protected research time: 2 years, 50% of the position

4 approvals

Rahel Goitein-Straus

Support for the transition of female physicians/researchers to their first independent research work; protected research time: 1 year, 50% of the position

4 approvals

Short-Term Grants

Support for research activities by women during or even after their residencies; protected research time: 3-6 months

4 approvals

Mentoring Program

For female researchers and physicians with modular management training and competency seminars as well as mentoring by experienced leaders

10 participants

Internal Research Support Programs




"Third-Party Funding“ Bonus Program

Researchers will receive a bonus for the acquisition of third-party funding for biomedical projects, which were awarded in a recognized evaluation procedure

About 4 million euros

Bonus Program Leading Publications

Bonus for publications on research results which were predominantly developed at a facility of the Medical Faculty at the University of Heidelberg

About 200 thousand euros

Research / Investment Funds

Funding from the German Research Foundation (DFG) overhead financing program to reinforce the research infrastructure. In 2019, the focus was on large-scale research equipment.

Up to 2 million euros